Berberine - a natural compound with numerous health benefits

Oct 22, 2024
Cover photo. Berberine - a natural compound with numerous health benefits_Berberine plant

When it comes to fitness and performance supplements, berberine has become a widely appreciated natural compound due to its numerous health benefits. In this article, we will detail how berberine can help athletes and fitness enthusiasts improve their performance, promote post-workout recovery, maintain a healthy body composition, and other essential information.


Contents:

  1. Berberine - what is it and which plants contain this natural compound?
  2. Berberine, contraindications and precautions
  3. Berberine, benefits and relevant studies on its use + dosage recommendations

1. Berberine - what is it and which plants contain this natural compound?

This natural compound extracted from various plants, such as Berberis vulgaris, is known for its antioxidant, anti-inflammatory properties and ability to support metabolic health.

What is berberine? Berberine is a natural compound, an alkaloid extracted from several plant species, known for its therapeutic properties and multiple health benefits. In traditional Chinese and Ayurvedic medicine, berberine has been used for centuries to relieve infections, digestive disorders, and other inflammatory conditions.

Plants containing berberine:

Berberine is found naturally in several plant species known for their therapeutic uses. Among the most important plants containing berberine are:

  • Berberis vulgaris (Barberry) - this is one of the most common sources of berberine. The plant has been used for centuries in traditional medicine to manage infections, inflammation, and digestive disorders.
  • Hydrastis canadensis (Goldenseal) - is another rich source of berberine, traditionally used to improve respiratory conditions and inflammation.
  • Coptis chinensis (Chinese Coptis) - is a plant frequently used in traditional Chinese medicine for the management and improvement of bacterial and fungal infections.
  • Phellodendron amurense (Amur Tree) - this supplemental source of berberine is usually used traditionally for its antimicrobial and anti-inflammatory properties.

These plants contain different concentrations of berberine, but all are recognized for their beneficial effects on health. Current berberine supplements, such as those we offer you in our online store, Nutriland, are obtained from standardized extracts of these plants, and more, to ensure a high content of berberine in each dose.

2. Berberine, contraindications and precautions

Although berberine has numerous health benefits, there are also certain contraindications and precautions that must be considered, especially for athletes or people using other supplements or medications.

Contraindications and precautions of berberine:

Interactions with diabetes medications : One of the most important things to consider is that berberine may lower blood sugar levels. For people already taking diabetes medications or other therapies, such as insulin or oral antidiabetic drugs, using berberine may cause blood sugar levels to drop too low (hypoglycemia). It is essential to consult a doctor before adding berberine to your supplement regimen, especially if you are already taking diabetes therapy.

Interactions with cholesterol medications : Berberine has a similar effect to statins in lowering cholesterol levels. This means it may enhance the effect of medications prescribed for high cholesterol.

Such a combination may lead to an excessive decrease in LDL cholesterol, which may affect the body's lipid balance. Consulting a specialist is necessary in this case, for the correct adjustment of the treatment.

Adverse or side effects of berberine : For some people, berberine can cause gastrointestinal side effects, such as abdominal cramps, diarrhea, or constipation. These effects usually occur with high doses, and lowering the dose or taking it with food may reduce symptoms. Therefore, careful monitoring is recommended when starting treatment.

Precautions for pregnant or breastfeeding women : There is not enough clinical evidence to support the safety of berberine during pregnancy or breastfeeding. Therefore, pregnant or breastfeeding women should avoid this supplement unless prescribed by a healthcare professional.

3. Berberine, benefits and relevant studies on its use + dosage recommendations

Benefits of Berberine - About berberine we can say that it is a natural supplement appreciated for its numerous benefits on the health of the body, with a significant impact in supporting physical performance and body composition. These effects are largely due to its antioxidant, anti-inflammatory properties and ability to support metabolic health.

Benefits and effects of berberine for athletes and fitness enthusiasts:

This compound has also become popular among athletes and fitness enthusiasts, due to its beneficial effects on metabolic and cardiovascular health, and improved body composition.

One of the main reasons berberine is valued by athletes is its ability to support metabolic health, regulating blood sugar levels and improving insulin sensitivity.

This aspect is especially important for people who practice intense training, because an uncontrolled fluctuation in blood sugar can affect energy levels and, implicitly, physical performance.

Berberine works by activating AMP-activated protein kinase (AMPK). Through this activation, berberine helps muscle cells absorb glucose more efficiently, maintaining energy stability during workouts and preventing excessive fat accumulation.

3. Berberine, benefits and relevant studies on its use + dosage recommendations_Food supplement bottles, centimeter

Another major benefit of berberine is its anti-inflammatory and antioxidant effects. Athletes, especially those who train intensely or practice endurance sports, are subject to high levels of oxidative stress. This can lead to tissue inflammation and damage to muscle fibers.

Berberine helps reduce this oxidative stress, protecting muscle cells from damage and accelerating the post-workout recovery process. These properties are essential for maintaining joint health and flexibility, but also for preventing injuries that occur due to chronic inflammation.

Does berberine help with weight loss?

Additionally, berberine supports fat burning, an essential process for athletes looking to optimize their body composition. Berberine helps inhibit the formation of new fat cells, but also breaks down existing fat, thus facilitating weight loss. This is beneficial for people looking to both reduce body fat for a more defined figure and increase muscle mass.

Weight loss supplements are also very beneficial in this regard, contributing to an optimal body weight. In addition, in addition to a healthy lifestyle, you can include in your diet hepatoprotective supplements to maintain liver health, as well as cholesterol supplements to lower triglycerides and increase "good" cholesterol, HDL. Moreover, antioxidant supplements have the ability to fight the negative effects of free radicals and maintain the health of the body's cells.

Berberine helps regulate blood lipid levels, especially by reducing LDL cholesterol, the "bad" cholesterol, and triglycerides, as well as increasing HDL cholesterol, the "good" cholesterol.

These effects have a direct impact on cardiovascular health, which is essential for optimal physical performance. Reducing high cholesterol and triglyceride levels prevents the formation of atherosclerotic plaques and helps maintain the flexibility of blood vessels. This improves the flow of oxygen and nutrients to the muscles during intense physical exertion.

Cardiovascular health is fundamental for athletes, as the heart and circulatory system must be able to withstand prolonged exertion. Berberine has beneficial effects on endothelial function, reducing arterial stiffness and improving blood circulation. This promotes better oxygenation of the muscles, an important factor for performance in endurance sports or high-intensity training.

Berberine also helps regulate blood pressure, which can be helpful for athletes, especially those who engage in high-intensity cardiovascular training. Maintaining healthy blood pressure helps prevent strokes and supports stable physical performance.

Berberine is a well-documented supplement, with numerous studies confirming its benefits in various areas of health, including sports nutrition.

Relevant studies on the power of berberine and athletic performance

Berberine and metabolic health : A 2008 study published in “Metabolism - Clinical and Experimental” looked at the effects of berberine on patients with type 2 diabetes and dyslipidemia. (3)

This study is extremely relevant to athletes, as it demonstrated that berberine can reduce blood sugar levels and improve insulin sensitivity. Berberine was also found to lower LDL cholesterol and triglyceride levels, factors that contribute to overall metabolic health, which is essential for those involved in regular physical activity.

Berberine and weight loss : Another 2012 study showed that berberine may contribute to weight loss and improve body composition. (4)

Overweight study participants were given 500 mg of berberine three times a day for 12 weeks. At the end of the study, a significant reduction in body weight and body mass index (BMI) was observed. This could be extremely valuable for individuals or athletes looking to reduce body fat and optimize performance.

Anti-inflammatory and antioxidant effects : A 2014 study also showed that berberine has strong anti-inflammatory and antioxidant effects. (5)

The study highlighted berberine's ability to reduce levels of pro-inflammatory proteins, such as TNF-alpha and IL-6, contributing to faster muscle tissue recovery after intense workouts. This effect is especially valuable for athletes who practice strength or endurance training, where inflammation and oxidative stress are common.

How is berberine taken?

The recommended dosage for berberine varies, depending on each person's goals and health status. However, most studies have used doses of 500 mg 2-3 times daily, which equates to a total of 1000-1500 mg daily.

For blood sugar control and metabolic health : The standard recommended dose is 500 mg, taken two to three times daily, before meals. This dosage has been shown in clinical studies to help regulate blood sugar levels and improve insulin sensitivity. Athletes may benefit from this regimen to optimize their energy levels and avoid glycemic fluctuations that could affect athletic performance.

For supporting cardiovascular health : Doses of 1000-1500 mg per day have shown positive effects on reducing LDL cholesterol and triglycerides, improving heart and circulatory health. This is essential for athletes who engage in intense cardiovascular training, where optimal cardiac function is essential.

To support muscle recovery and reduce inflammation : A dose of 500 mg twice daily has been associated with a reduction in inflammation and oxidative stress, which may speed up post-workout recovery and prevent injury. Especially for those who are strength training or cross-training, this dose may support long-term muscle and joint health.

Tips for the correct administration of berberine

It is recommended that berberine be taken approximately 30 minutes before meals. This increases absorption and its effects on blood glucose and lipid levels.

Because berberine has a relatively short duration of action in the body, it is advisable to administer it in divided doses throughout the day, 2-3 times, to maintain a constant effect.

It is essential to avoid taking berberine in combination with other supplements or medications that affect blood sugar or cholesterol without first consulting a doctor. Interactions can amplify the effects and lead to complications.

In conclusion, berberine is an effective and versatile supplement for athletes looking to improve metabolic health, optimize recovery, and enhance physical performance. It is also suitable for people who want to follow an active and healthy lifestyle.

Given its ability to regulate blood sugar and lipids, its antioxidant and anti-inflammatory properties, berberine provides valuable support for a well-balanced diet. For people looking to improve body composition, increase exercise endurance and optimize cardiovascular health, berberine is a supplement worth considering.

References:

  1. https://www.healthline.com/nutrition/berberine-powerful-supplement#blood-sugar-regulation
  2. https://medlineplus.gov/druginfo/natural/1126.html
  3. https://academic.oup.com/jcem/article/93/7/2559/2598635
  4. https://elo.health/articles/what-you-need-to-know-about-berberine-supplementation/
  5. https://link.springer.com/article/10.1007/s00210-021-02182-3

Photo sources: Pexels, Shutterstock


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